Endocrine Abstracts

Purpose: 111In-octreotide scinti aphy may be useful in patients with insulinoma during pre-surgical localization of the tumor and octreotide is effective in inhibiting insulin secretion and reducing the hypoglycemic events. The aim of the study was to evaluate 111in-octreotide scintigraphy in localizing primary and metastatic insulinomas and predicting the response to octreotide administration.Patients and methods: Diagnosis of insulinoma was made in 17 ...

Background: Levothyroxine is the standard treatment for central hypothyroidism (CH). Studies assessing the optimal dose are limited and include subjects with other untreated pituitary hormone deficits, affecting the interpretation of results. A reliable comparison with the dose used in primary hypothyroidism (PH) has not been reported.Aims: To evaluate daily and body-weight-adapted levothyroxine dose (BWA-dose) in a cohort of patients with CH on appropri...

Background: Cabergoline is effective in achieving normoprolactinaemia and tumour shrinkage in about 70% of patients with macroprolactinoma. Only a few studies have followed-up the adenoma shrinkage for periods >2 years;the need for continuing imaging thereafter is not certain.Aim: To evaluate tumour volume changes in patients with macroprolactinoma responsive to cabergoline during a long follow-up period.Patients and methods: M...